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It is also reported that GLP‐1‐producing NTS neurons project directly to the VTA and NAc (core and shell) (Alhadeff et al., 2012) and that GLP‐1 receptor activation of the NTS alters expression of dopamine‐related genes in the VTA (Richard et al., 2015) However, the growing number of brain regions that have shown a positive effect upon GLP‐1 agonist infusion does not immediately suggest a clear and defined circuit‐level mechanism
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