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Since we’ve touched on chromatography for peptide analysis, it’s worth noting that peptides are prone to adsorption onto surfaces during analysis (often due to ionic or dipole–dipole interactions with metals in the LC flow path), reducing sensitivity and compromising the accurate quantification of low-level impurities
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Tirzepatide is already approved for glycemic control in T2D, showing clinically significant reductions in HbA1c from baseline [47, 48]
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