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Is there a link between GLP-1RA use & thyroid cancer? A study co-auther by EGDRC members, published in @JAMA_current found a short-term association between GLP-1RA initiation and thyroid cancer diagnosis, likely due
“On average, patients can expect to lose one to three pounds per week,” she says
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The clinical implication of that β-arrestin-sparing profile is still under investigation, but NIH-funded research published in Nature in May 2026 found that small-molecule GLP-1 drugs access reward circuits deep within the brain — circuits involved in hedonic, pleasure-driven feeding — through pathways that the larger peptide molecules do not reach, suggesting the two drug classes may suppress appetite through partially distinct neural mechanisms
