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GLP-1 agonist Exendin-4 upregulates some genes when PASK is inactivated, such as nuclear factor erythroid 2-related factor 2 (NRF2) and copper–zinc superoxide dismutase (SOD), and others independent of PASK status, such as peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPargc1a) [144]
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