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They do not appear to silence mast cells directly but instead shield the surrounding neurons from their inflammatory impact, preserving communication in the gut–brain axis

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Methylmalonic acid is a more sensitive marker of functional B12 status Complete blood count (CBC): Establishes baseline red blood cell parameters for monitoring anemia development Iron panel (ferritin, serum iron, TIBC): Ferritin below 30 ng/mL suggests depleted stores even with normal hemoglobin Comprehensive metabolic panel: Includes calcium, magnesium (though serum magnesium is imperfect), and kidney function RBC magnesium: More accurate than serum magnesium